Longevity pharmacology (metformin, rapamycin, etc.)

Emerging evidence

Longevity pharmacology covers prescription drugs — such as metformin and rapamycin — being studied for their potential to influence the biology of aging, often through off-label use under medical supervision. Clinics offer assessment, prescribing and monitoring within structured programmes.

Updated 30 June 2026

What longevity pharmacology involves

This category covers established prescription medicines — most prominently metformin and rapamycin (sirolimus) — that researchers are investigating for effects on aging-related pathways. In a clinic setting they are typically used off-label, meaning for a purpose other than their original approval, with screening, dosing and monitoring handled by a physician.

What to consider when choosing a clinic

Evidence in humans is still developing and these drugs carry real risks and contraindications, so medical supervision is essential. Look for clinics that screen thoroughly, explain off-label status and the current evidence honestly, and provide ongoing monitoring. Never source prescription longevity drugs without a qualified prescriber.

The clinics listed below work with longevity pharmacology — compare locations, services and reviews. For how researchers are identifying repurposable drugs that target the hallmarks of aging, read our in-depth guide.

In-depth guide Read the full guide on Longevity pharmacology (metformin, rapamycin, etc.)

Clinics offering Longevity pharmacology (metformin, rapamycin, etc.)

7 clinics

Unlimited Bio

Unlimited Bio

Próspera ZEDE, United StatesMedical
4.6(141 reviews)
Longevity pharmacology (metformin, rapamycin, etc.)

English

ZOIME

ZOIME

Dubai, United Arab EmiratesMedical
5.0(36 reviews)
IV nutrient therapyNAD+ infusionsHormone optimization+10

English · French

Chi Longevity

Chi Longevity

Singapore, SingaporeMedical
5.0(6 reviews)
Hormone optimizationPersonalized nutrition programsExercise and performance programs+3

English

BelleCell

BelleCell

City of Westminster, United KingdomMedical
New listing
IV nutrient therapyNAD+ infusionsHormone optimization+12
Biongevity

Biongevity

Calgary, CanadaMedical
New listing
IV nutrient therapyNAD+ infusionsHormone optimization+13

English

Healthy Longevity Clinic

Healthy Longevity Clinic

Prague, CzechiaMedical
New listing
IV nutrient therapyNAD+ infusionsHormone optimization+10

Czech · English

Origin Health Basel

Origin Health Basel

Basel, SwitzerlandMedical
New listing
IV nutrient therapyNAD+ infusionsGLP-1 therapy+7

Showing 7 of 7 clinics

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Frequently asked questions

What is longevity pharmacology?
It refers to the use of prescription drugs — such as metformin and rapamycin — that are being studied for potential effects on the biology of aging, usually prescribed off-label and monitored by a physician.
Do drugs like metformin and rapamycin slow aging?
There are promising mechanisms and ongoing trials, but it is not yet proven that these drugs extend healthy lifespan in humans. They should only be considered with a clinician who can weigh the evidence and risks for your situation. Our guide covers the latest research.
Is off-label use of these drugs safe?
Off-label prescribing is legal and common in medicine, but these drugs have side effects and contraindications. Safety depends on proper screening, dosing and monitoring by a qualified prescriber.
How much does a longevity pharmacology programme cost?
Costs depend on the clinic, the medications and the level of testing and monitoring involved. Request a full quotation and confirm what follow-up is included.
Where can I access longevity pharmacology?
Browse the verified clinics listed on this page, then contact a provider directly to discuss eligibility, screening and monitoring with a medical professional.
What does the "Emerging evidence" rating mean for Longevity pharmacology (metformin, rapamycin, etc.)?
We rate Longevity pharmacology (metformin, rapamycin, etc.) "Emerging": there is a plausible biological mechanism and early or limited human data, but not yet robust long-term trials with hard outcomes — promising, but not proven. Our ratings are a simplified mapping of recognised evidence-grading systems such as GRADE and the Oxford CEBM levels of evidence. How we rate evidence